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| Leontis / Westhof Classification Legend* |
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| No. |
Glycosidic bond orientation |
Interacting edges |
Local strand orientation |
| 1 |
Cis |
Watson-Crick/Watson-Crick |
Antiparallel |
| 2 |
Trans |
Watson-Crick/Watson-Crick |
Parallel |
| 3 |
Cis |
Watson-Crick/Hoogsteen |
Parallel |
| 4 |
Trans |
Watson-Crick/Hoogsteen |
Antiparallel |
| 5 |
Cis |
Watson-Crick/Sugar
Edge |
Antiparallel |
| 6 |
Trans |
Watson-Crick/Sugar
Edge |
Parallel |
| 7 |
Cis |
Hoogsteen/Hoogsteen |
Antiparallel |
| 8 |
Trans |
Hoogsteen/Hoogsteen |
Parallel |
| 9 |
Cis |
Hoogsteen/Sugar
Edge |
Parallel |
| 10 |
Trans |
Hoogsteen/Sugar
Edge |
Antiparallel |
| 11 |
Cis |
Sugar Edge/Sugar Edge |
Antiparallel |
| 12 |
Trans |
Sugar
Edge/Sugar Edge |
Parallel |
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The 12 main families of base pairs between nucleic acid
bases together with the local strand orientation (which assumes that
all bases are in the default anti conformation: a syn
orientation would imply a reversal of orientation; for the global
orientation, the stereochemistry at the phophate groups has to be considered).
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* Leontis N, Westhof E. 2001.
Geometric nomenclature and classification of RNA base pairs.
RNA 7:499-512.
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©1995-2003 The Nucleic Acid Database Project
Rutgers, The State University of New Jersey
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