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| Title: | | THE SOLUTION NMR STRUCTURE OF THE C10R ADDUCT OF BENZO[A]PYRENE-DIOL-EPOXIDE AT THE N6 POSITION OF ADENINE OF AN 11 BASE-PAIR OLIGONUCLEOTIDE SEQUENCE CODING FOR AMINO ACIDS 60-62 OF THE PRODUCT OF THE N-RAS PROTOONCOGENE, MINIMIZED AVERAGE STRUCTURE | |
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| Molecular Description: | 5'-D(CpGpGpApCp(E)pApGpApApG)-3'
5'-D(CpTpTpCpTpTpGpTpCpCpG)-3' |
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| Nucleic Acid Sequence: |
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| Chain | A: | | (DC) (DG) (DG) (DA) (DC) E (DA) (DG) (DA) (DA) (DG) |
| Chain | B: | | (DC) (DT) (DT) (DC) (DT) (DT) (DG) (DT) (DC) (DC) (DG) |
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| Primary Citation: | Zegar, I.S., Kim, S.J., Johansen, T.N., Horton, P.J., Harris, C.M., Harris, T.M., Stone, M.P.
Adduction of the human N-ras codon 61 sequence with (-)-(7S,8R,9R,10S)-7,8-dihydroxy-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a] pyrene: structural refinement of the intercalated SRSR(61,2) (-)-(7S,8R,9S,1 0R)-N6-[10-(7,8,9,10- tetrahydrobenzo[a]pyrenyl)]-2'-deoxyadenosyl adduct from 1H NMR
Biochemistry
, 35,
pp. 6212 - 6224, 1996.
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Experimental Information: | SOLUTION NMR |
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Number of Models: | 1 Model |
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