 | | | |
| Title: | | THE SOLUTION STRUCTURE OF A NON-BAY REGION 11R-BENZ[A]ANTHRACENE OXIDE ADDUCT AT THE N6 POSITION OF ADENINE OF AN OLIGODEOXYNUCLEOTIDE CONTAINING THE HUMAN N-RAS CODON 61 SEQUENCE | |
|
| Molecular Description: | 5'-D(CpGpGpApCpApApGpApApG)-3'
5'-D(CpTpTpCpTpTpGpTpCpCp G)-3' |
 |
| Nucleic Acid Sequence: |
| | | |
| Chain | A: | | (DC) (DG) (DG) (DA) (DC) (DA) (DA) (DG) (DA) (DA) (DG) |
| Chain | B: | | (DC) (DT) (DT) (DC) (DT) (DT) (DG) (DT) (DC) (DC) (DG) |
|
|
| Primary Citation: | Li, Z., Kim, H.Y., Tamura, P.J., Harris, C.M., Harris, T.M., Stone, M.P.
Role of a polycyclic aromatic hydrocarbon bay region ring in modulating DNA adduct structure: the non-bay region (8S,9R,10S, 11R)-N(6)-[11-(8,9,10,11-tetrahydro-8,9, 10-trihydroxybenz[a]anthracenyl)]-2' -deoxyadenosyl adduct in codon 61 of the human N-ras protooncogene
Biochemistry
, 38,
pp. 14820 - 14832, 1999.
|
|
| | | |
|
Experimental Information: | SOLUTION NMR |
|
|
Number of Models: | 1 Model |
|
| Sample Details: |
1.8 mM oligodeoxynucleotide; 10 mM phosphate buffer; 0.05 mM EDTA; 0.1 M NaCl
90% H2o. 10% D2o
|
|
|
|
