PDB ID: 1EI2


Title:STRUCTURAL BASIS FOR RECOGNITION OF THE RNA MAJOR GROOVE IN THE TAU EXON 10 SPLICING REGULATORY ELEMENT BY AMINOGLYCOSIDE ANTIBIOTICS
Nucleic Acid Sequence:
ChainA: G G C A G U G U G A G U A C C U U C A C A C G U C
Primary Citation:Varani, L., Spillantini, M.G., Goedert, M., Varani, G.
Structural basis for recognition of the RNA major groove in the tau exon 10 splicing regulatory element by aminoglycoside antibiotics.
Nucleic Acids Res. , 28, pp. 710 - 719, 2000.
Experimental Information:NMR
Number of Models:17 STRUCTURES
Sample Details: 1mM tau exon 10 SRE RNA U-13C,15N; 10mM phosphate buffer, pH 6; 1mM neomycin unlabelled 90% H2O, 10% D2O

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Coordinates

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Derivative Data

Nucleic Acid Backbone Torsions

Base Pair Parameters

Base Pair Step Parameters

Hydrogen Bonding Classification

Links

The Protein Data Bank: 1EI2

PubMed: 10637322




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