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| Title: | | SOLUTION STRUCTURE OF R-STYRENE ADDUCT IN THE RAS61 SEQUENCE | |
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| Molecular Description: | 5'-D(CpGpGpApCp(ABR)pApGpApApG)-3' |
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| Nucleic Acid Sequence: |
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| Chain | A: | | (DC) (DG) (DG) (DA) (DC) (ABR) (DA) (DG) (DA) (DA) (DG) |
| Chain | B: | | (DC) (DT) (DT) (DC) (DT) (DT) (DG) (DT) (DC) (DC) (DG) |
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| Primary Citation: | Hennard, C., Finneman, J., Harris, C.M., Harris, T.M., Stone, M.P.
The nonmutagenic (R)- and (S)-beta-(N(6)-adenyl)styrene oxide adducts are oriented in the major groove and show little perturbation to DNA structure.
Biochemistry
, 40,
pp. 9780 - 9791, 2001.
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Experimental Information: | SOLUTION NMR |
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Number of Models: | 1 Model |
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| Sample Details: |
130 OD260 of double stranded oligodeoxynucleotide are dissolved in 0.5 ml nmr buffer containing 99.996% D2O.
The buffer is 10mM sodium phosphate pH 6.9 containing 100mM NaCl and 0.05mM Na2EDTA.
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