1 101 276 277 278 279 280 281 282 283 284 285 286 287 288 289 290 291 292 293 294 295 296 297 298 299 300 301 302 303 304 305 306 307 308 309 310 311 312 313 314 315 316 317 318 319 320 321 322 323 324 325 326 327 328 329 330 331 332 333 334 335 336 337 338 339 340 341 342 343 344 345 346 347 348 349 350 351 352 353 354 355 356 357 358 359 360 361 362 363 364 365 366 367 368 369 370 371 372 373 374 375 376 GGCGGUaCUA GUUGAGAAAC UAGCUCUGUA UCUGGCGGAC CCGUGGUGGA ACUGUGAAGU UCGGAACACC CGGCCGCAAC CCUGGGAGAG GUCCCAGGGU U 7 AP7 LOOP1 15 16 LOOP2 88 91 LOOP3 55 56 Crystallography ? ? Angstroms 1 G P 71.568 3.563 -31.637 O3' 70.971 4.370 -26.739 2 G P 71.923 3.214 -26.176 O3' 71.028 0.079 -22.333 3 C P 72.312 -0.861 -22.507 O3' 71.355 -5.579 -20.093 4 G P 72.714 -6.403 -20.277 O3' 71.931 -11.713 -20.298 5 G P 73.394 -12.275 -20.619 O3' 74.297 -16.726 -23.522 6 U P 75.890 -16.662 -23.666 O3' 77.866 -18.303 -27.827 7 a O3' 82.747 -17.352 -31.383 P 79.315 -18.146 -27.169 8 C P 84.162 -17.057 -30.696 O3' 86.610 -13.393 -33.938 9 U P 87.995 -13.011 -33.234 O3' 89.707 -8.401 -33.930 10 A P 91.031 -8.311 -33.036 O3' 92.776 -3.930 -30.418 11 G P 94.050 -4.260 -29.509 O3' 95.174 -2.324 -24.906 12 U P 96.408 -3.195 -24.381 O3' 96.574 -3.508 -19.116 13 U P 97.903 -4.364 -18.871 O3' 97.947 -7.762 -15.150 14 G P 99.470 -8.106 -15.499 O3' 100.452 -13.090 -15.254 15 A P 101.983 -12.856 -15.653 O3' 100.798 -15.363 -20.558 16 G P 99.335 -15.549 -21.177 O3' 96.141 -19.749 -21.977 17 A P 95.543 -18.767 -23.090 O3' 90.409 -20.648 -23.032 18 A P 88.952 -20.077 -22.700 O3' 86.693 -18.197 -18.130 19 A P 85.668 -16.968 -18.105 O3' 84.653 -12.848 -15.332 20 C P 83.411 -12.315 -16.189 O3' 83.299 -7.125 -15.843 21 U P 81.947 -6.878 -16.664 O3' 82.084 -2.274 -19.269 22 A P 80.742 -2.293 -20.140 O3' 81.432 0.387 -24.629 23 G P 80.267 0.230 -25.714 O3' 80.153 -0.223 -30.819 24 C P 78.556 -0.248 -30.904 O3' 77.204 -3.643 -34.760 25 U P 75.640 -3.768 -35.075 O3' 74.229 -8.082 -37.488 26 C P 72.766 -7.485 -37.745 O3' 69.661 -12.095 -37.391 27 U P 68.134 -11.631 -37.502 O3' 65.191 -13.611 -34.127 28 G P 63.998 -12.724 -34.721 O3' 60.936 -11.459 -30.683 29 U P 59.951 -10.362 -31.303 O3' 58.266 -7.948 -26.708 30 A P 56.814 -8.017 -27.380 O3' 54.928 -4.299 -24.332 31 U P 53.528 -4.992 -24.678 O3' 49.567 -0.919 -25.612 32 C P 48.474 -1.537 -26.604 O3' 44.413 1.974 -25.812 33 U P 43.047 1.162 -25.619 O3' 40.161 3.883 -21.871 34 G P 39.550 5.198 -22.547 O3' 37.933 8.502 -23.578 35 G P 37.112 7.695 -24.690 O3' 38.997 7.533 -29.480 36 C P 38.343 8.920 -29.935 O3' 37.415 8.854 -35.037 37 G P 36.394 9.982 -35.531 O3' 32.391 9.080 -39.599 38 G P 31.051 9.872 -39.967 O3' 26.558 9.301 -40.600 39 A P 25.996 10.773 -40.873 O3' 20.748 11.097 -39.687 40 C P 19.908 12.452 -39.561 O3' 17.968 15.110 -34.818 41 C P 16.378 15.277 -34.885 O3' 14.341 14.934 -30.012 42 C P 14.317 16.481 -29.604 O3' 14.991 16.966 -24.312 43 G P 15.165 18.546 -24.118 O3' 17.563 20.233 -19.952 44 U P 16.612 21.457 -20.347 O3' 22.109 23.003 -19.714 45 G P 22.169 22.790 -18.129 O3' 25.695 21.974 -17.911 46 G P 26.191 23.494 -17.964 O3' 31.075 25.316 -18.827 47 U P 30.569 26.738 -18.295 O3' 33.359 30.305 -21.676 48 G P 32.823 31.765 -21.300 O3' 32.192 35.793 -24.316 49 G P 30.953 36.717 -23.900 O3' 27.945 37.431 -26.816 50 A P 28.661 38.825 -27.137 O3' 26.561 42.291 -30.149 51 A P 27.826 43.249 -29.945 O3' 25.984 48.743 -29.560 52 C P 27.049 49.769 -28.949 O3' 25.212 53.455 -25.678 53 U P 26.527 54.234 -25.205 O3' 26.524 56.575 -20.606 54 G P 27.860 57.446 -20.729 O3' 32.583 57.416 -17.777 55 U P 33.337 58.464 -18.722 O3' 37.617 54.755 -19.740 56 G P 37.050 53.259 -19.707 O3' 38.225 48.829 -16.811 57 A P 37.336 47.965 -17.821 O3' 35.634 44.349 -13.754 58 A P 34.497 43.390 -14.343 O3' 29.899 43.522 -12.260 59 G P 28.559 42.944 -12.917 O3' 23.842 46.130 -12.743 60 U P 22.481 45.532 -13.336 O3' 19.157 48.606 -16.054 61 U P 17.919 47.595 -16.143 O3' 15.299 47.751 -20.878 62 C P 14.332 46.484 -21.012 O3' 14.359 43.619 -25.667 63 G P 12.984 42.921 -25.241 O3' 13.214 37.642 -25.801 64 G P 12.174 36.886 -24.848 O3' 13.825 33.722 -20.562 65 A P 15.301 33.113 -20.461 O3' 16.037 30.163 -25.409 66 A P 17.247 29.383 -26.106 O3' 18.275 29.831 -31.273 67 C P 19.144 28.492 -31.155 O3' 22.856 28.985 -35.108 68 A P 23.389 27.485 -35.270 O3' 28.648 26.885 -35.698 69 C P 28.644 25.320 -36.027 O3' 32.822 22.594 -33.914 70 C P 32.444 21.041 -34.001 O3' 34.058 18.346 -29.226 71 C P 33.499 16.848 -29.161 O3' 31.971 15.170 -24.830 72 G P 31.932 13.710 -25.483 O3' 28.933 10.545 -22.192 73 G P 29.402 9.231 -22.975 O3' 24.472 6.456 -22.966 74 C P 24.847 5.114 -23.753 O3' 21.724 4.278 -27.473 75 C P 22.429 2.841 -27.442 O3' 22.389 0.937 -32.749 76 G P 23.046 -0.503 -32.515 O3' 26.463 -2.731 -35.558 77 C P 26.794 -3.891 -34.508 O3' 32.151 -5.137 -34.985 78 A P 31.746 -6.608 -34.500 O3' 36.458 -8.466 -32.104 79 A P 36.374 -9.449 -30.844 O3' 39.648 -9.050 -26.678 80 C P 39.187 -10.405 -25.962 O3' 38.653 -10.859 -20.776 81 C P 38.015 -12.326 -20.777 O3' 35.207 -12.050 -16.045 82 C P 34.419 -13.428 -15.857 O3' 30.858 -13.003 -12.280 83 U P 30.083 -14.389 -12.082 O3' 25.866 -16.251 -12.518 84 G P 26.361 -17.767 -12.387 O3' 22.418 -21.009 -13.939 85 G P 23.082 -22.326 -13.322 O3' 20.850 -26.176 -15.878 86 G P 21.399 -27.052 -14.656 O3' 22.169 -31.704 -17.209 87 A P 23.043 -32.532 -16.154 O3' 25.396 -36.390 -19.041 88 G P 26.685 -37.182 -18.523 O3' 31.340 -37.285 -21.537 89 A P 32.211 -38.513 -20.994 O3' 36.775 -36.988 -17.766 90 G P 37.311 -35.765 -18.646 O3' 39.734 -30.841 -15.915 91 G P 41.199 -30.201 -15.926 O3' 38.535 -27.285 -18.713 92 U P 38.743 -26.041 -19.697 O3' 36.537 -26.138 -24.760 93 C P 36.148 -24.611 -25.039 O3' 31.978 -24.650 -28.140 94 C P 32.254 -23.138 -28.581 O3' 27.824 -21.421 -30.103 95 C P 28.333 -19.924 -30.342 O3' 23.914 -17.211 -29.557 96 A P 24.417 -15.716 -29.827 O3' 21.155 -12.000 -27.304 97 G P 21.787 -10.535 -27.176 O3' 20.970 -7.187 -23.394 98 G P 21.872 -5.966 -23.901 O3' 23.462 -2.735 -20.107 99 G P 24.198 -1.506 -20.820 O3' 28.024 0.695 -17.850 100 U P 28.220 1.977 -18.787 O3' 33.220 3.395 -19.531 101 U P 33.141 4.584 -20.597 O3' 37.283 4.806 -24.175 64 syn 1 30 W W c 2 29 W W c 3 28 + + c 4 27 W W c 5 26 + + c 6 25 W W c 7 24 W W c 8 23 + + c 9 22 - - c 10 21 - - c 11 20 + + c 12 19 - - c 13 18 - - c 14 17 W H t 35 77 + + c 36 76 + + c 37 75 W W c 38 74 W W c 41 73 + + c 42 72 + + c 43 71 + + c 45 70 + + c 46 68 W W c 46 69 + + c 47 68 - - c 48 67 + + c 49 62 + + c 50 61 - - c 51 60 - - c 52 59 + + c 53 58 - - c 54 57 S H t 78 101 - - c 79 100 - - c 80 99 + + c 81 98 + + c 82 97 + + c 83 96 - - c 84 95 + + c 85 94 + + c 86 93 + + c 87 92 - - c 91 92 S H c 39 41 ! ! ! 50 60 ! ! ! 51 59 ! ! ! 14 16 ! ! ! 34 101 ! ! ! 40 41 ! ! ! 54 56 ! ! ! 1 30 14 45 70 4 41 73 3 35 77 4 78 101 10 49 62 6 SG1 15 16 SG2 31 34 SG3 39 40 SG4 44 44 SG5 55 56 SG6 63 66 SG7 88 91 1 217.187 342.376 2 201.944 346.618 3 186.701 350.859 4 171.457 355.101 5 156.214 359.342 6 140.970 363.584 7 125.727 367.825 8 110.484 372.067 9 95.240 376.308 10 79.997 380.550 11 64.753 384.792 12 49.510 389.033 13 34.267 393.275 14 19.023 397.516 15 0.000 410.550 16 6.182 432.766 17 29.203 434.100 18 44.446 429.859 19 59.690 425.617 20 74.933 421.376 21 90.176 417.134 22 105.420 412.893 23 120.663 408.651 24 135.907 404.410 25 151.150 400.168 26 166.393 395.927 27 181.637 391.685 28 196.880 387.444 29 212.124 383.202 30 227.367 378.961 31 236.513 376.416 32 245.659 373.871 33 254.805 371.326 34 263.951 368.781 35 461.953 344.363 36 461.953 328.540 37 461.953 312.718 38 461.953 296.895 39 461.953 281.073 40 461.953 265.250 41 461.953 249.428 42 461.953 233.605 43 461.953 217.783 44 461.953 201.960 45 461.953 186.138 46 461.953 170.315 47 461.953 154.493 48 461.953 138.670 49 454.160 93.895 50 443.190 82.492 51 432.221 71.090 52 421.251 59.688 53 410.281 48.285 54 399.311 36.883 55 389.557 15.988 56 406.175 0.000 57 426.677 10.555 58 437.647 21.958 59 448.617 33.360 60 459.586 44.762 61 470.556 56.165 62 481.526 67.567 63 423.980 100.696 64 423.980 110.190 65 423.980 119.683 66 423.980 129.177 67 423.980 138.670 68 423.980 154.493 69 423.980 170.315 70 423.980 186.138 71 423.980 217.783 72 423.980 233.605 73 423.980 249.428 74 423.980 296.895 75 423.980 312.718 76 423.980 328.540 77 423.980 344.363 78 423.980 376.008 79 423.980 391.830 80 423.980 407.653 81 423.980 423.475 82 423.980 439.298 83 423.980 455.120 84 423.980 470.943 85 423.980 486.765 86 423.980 502.588 87 423.980 518.410 88 421.840 536.432 89 433.892 550.000 90 452.041 550.000 91 464.093 536.432 92 461.953 518.410 93 461.953 502.588 94 461.953 486.765 95 461.953 470.943 96 461.953 455.120 97 461.953 439.298 98 461.953 423.475 99 461.953 407.653 100 461.953 391.830 101 461.953 376.008