PDB ID: 1Y9H
Title: METHYLATION OF CYTOSINE AT C5 IN A CPG SEQUENCE CONTEXT CAUSES A CONFORMATIONAL SWITCH OF A BENZO[A]PYRENE DIOL EPOXIDE-N2-GUANINE ADDUCT IN DNA FROM A MINOR GROOVE ALIGNMENT TO INTERCALATION WITH BASE DISPLACEMENT Molecular Description: 5'-D(CpCpApTp(5CM)pGpCpTpApCp C)-3'/ 5'-D(GpGpTpApGpCpGpApTpGpG)-3' Nucleic Acid Sequence: Chain A: (DC) (DC) (DA) (DT) (5CM) (DG) (DC) (DT) (DA) (DC) (DC) Chain B: (DG) (DG) (DT) (DA) (DG) (DC) (DG) (DA) (DT) (DG) (DG) Primary Citation: Zhang, N., Lin, C., Huang, X., Kolbanovskiy, A., Hingerty, B.E., Amin, S., Broyde, S., Geacintov, N.E., Patel, D.J. Methylation of cytosine at C5 in a CpG sequence context causes a conformational switch of a benzo[a]pyrene diol epoxide-N2-guanine adduct in DNA from a minor groove alignment to intercalation with base displacement. J.Mol.Biol. , 346, pp. 951 - 965, 2005. Experimental Information: SOLUTION NMR Number of Models: 9 Structures Sample Details: 11mer DNA duplex with MeC5 and [BP]G6 modified, H2O and D2O H2O and D2O	Representative Model Other Views Ensemble Enlarge Representative Model
Coordinates Coordinates (pdb format, Unix compressed(.gz)) Coordinates (cif format, Unix compressed(.gz)) NMR Restraints (cif format, Unix compressed(.gz)) XML | Complete with coordinates (xml format, GNU compressed(.gz)) XML | Coordinates only (xml format, GNU compressed(.gz)) XML | Header only (xml format, GNU compressed(.gz))	Derivative Data Nucleic Acid Backbone Torsions Base Pair Parameters Base Pair Step Parameters Hydrogen Bonding Classification
Links
The RCSB Protein Data Bank: 1Y9H
PubMed: 15701509
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