1 43 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 GGGAUAUGGA AGAACCGGGG AAACUUGGUU CUUCCUAAGU CCU LOOP1 21 22 Crystallography ? ? Angstroms 1 G O3' 9.956 40.266 3.728 2 G P 9.464 38.734 3.637 O3' 5.641 37.391 7.271 3 G P 5.529 35.785 7.269 O3' 0.717 34.105 8.884 4 A P 0.648 32.498 8.965 O3' -3.812 29.994 7.896 5 U P -3.753 28.386 7.947 O3' -5.768 25.212 3.984 6 A P -5.556 23.617 4.018 O3' -7.074 20.722 -1.203 7 U P -7.715 19.457 -1.969 O3' -4.016 18.285 -6.832 8 G P -2.686 17.431 -7.148 O3' 0.895 15.411 -5.919 9 G P 0.114 14.066 -6.337 O3' 0.351 10.616 -1.932 10 A P -0.592 9.312 -1.999 O3' -1.218 6.087 2.137 11 A P -2.376 4.969 2.058 O3' -4.150 2.822 6.798 12 G P -4.948 1.535 6.245 O3' -9.625 0.105 8.800 13 A P -10.237 -1.116 7.947 O3' -15.226 -1.373 7.371 14 A P -15.698 -2.476 6.294 O3' -20.546 -2.578 3.906 15 C P -20.635 -3.892 2.979 O3' -22.975 -4.088 -1.797 16 C P -22.669 -5.603 -2.253 O3' -20.685 -6.361 -7.123 17 G P -19.988 -7.781 -7.417 O3' -16.957 -8.842 -11.680 18 G P -16.267 -10.297 -11.639 O3' -11.364 -11.102 -13.161 19 G P -10.779 -12.600 -13.069 O3' -6.120 -14.364 -11.889 20 G P -6.070 -15.972 -11.927 O3' -6.592 -19.787 -8.210 21 A P -7.365 -21.131 -8.652 O3' -11.528 -21.767 -4.520 22 A P -12.209 -20.781 -3.445 O3' -10.755 -17.944 0.997 23 A P -10.928 -16.459 1.592 O3' -7.511 -13.112 5.040 24 C P -8.390 -11.766 5.136 O3' -4.314 -8.164 3.498 25 U P -4.645 -6.594 3.383 O3' -3.335 -4.176 -1.217 26 U P -3.597 -2.596 -1.047 O3' -4.525 -0.124 -5.453 27 G P -4.945 1.411 -5.202 O3' -8.966 2.937 -8.662 28 G P -9.191 4.517 -8.452 O3' -13.186 7.341 -9.268 29 U P -12.949 8.605 -8.296 O3' -16.509 10.969 -5.227 30 U P -15.918 12.087 -4.228 O3' -18.413 13.342 0.332 31 C P -17.604 14.461 1.159 O3' -17.168 13.736 6.580 32 U P -16.398 15.035 7.144 O3' -13.000 15.017 11.250 33 U P -12.058 16.317 11.357 O3' -7.194 15.498 13.923 34 C P -6.002 16.573 14.051 O3' -0.497 16.443 12.287 35 C P 0.632 17.574 12.085 O3' 5.421 18.258 9.432 36 U P 6.183 19.589 8.944 O3' 7.252 22.755 5.127 37 A P 7.598 24.228 4.580 O3' 6.162 26.348 -1.075 38 A P 7.700 26.170 -1.514 O3' 7.200 28.230 -6.801 39 G P 6.555 29.625 -7.280 O3' 1.058 31.314 -8.751 40 U P 0.627 32.864 -8.675 O3' -4.459 34.800 -7.902 41 C P -4.291 36.401 -7.926 O3' -7.255 39.038 -4.312 42 C P -6.961 40.621 -4.307 O3' -7.472 42.709 0.528 43 U P -7.224 44.295 0.652 O3' -4.585 45.775 5.237 7 syn 1 43 W W c 2 42 + + c 3 41 + + c 4 40 - - c 5 39 W W c 6 36 H W t 8 35 + + c 9 34 + + c 10 33 - - c 11 32 - - c 12 31 + + c 13 30 - - c 14 29 - - c 15 28 + + c 16 27 + + c 17 26 W W c 18 25 W W c 19 24 + + c 20 23 S H t 37 38 S H c 7 39 ! ! ! 1 43 5 8 35 13 SG1 6 7 SG2 21 22 SG3 36 38 1 157.254 0.000 2 157.254 17.335 3 157.254 34.670 4 157.254 52.006 5 157.254 69.341 6 157.254 86.676 7 157.254 121.346 8 157.254 173.352 9 157.254 190.687 10 157.254 208.022 11 157.254 225.357 12 157.254 242.693 13 157.254 260.028 14 157.254 277.363 15 157.254 294.698 16 157.254 312.033 17 157.254 329.369 18 157.254 346.704 19 157.254 364.039 20 157.254 381.374 21 165.424 405.281 22 190.688 405.281 23 198.858 381.374 24 198.858 364.039 25 198.858 346.704 26 198.858 329.369 27 198.858 312.033 28 198.858 294.698 29 198.858 277.363 30 198.858 260.028 31 198.858 242.693 32 198.858 225.357 33 198.858 208.022 34 198.858 190.687 35 198.858 173.352 36 198.858 156.017 37 198.858 138.681 38 198.858 104.011 39 198.858 69.341 40 198.858 52.006 41 198.858 34.670 42 198.858 17.335 43 198.858 0.000 1 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 GGGAUAU GGAAGAACCG GGGAAACUUG GUUCUUCCUA AGUCCU LOOP2 21 22 Crystallography ? ? Angstroms 1 G O3' -10.029 -39.639 3.297 2 G P -9.410 -38.157 3.168 O3' -5.606 -37.401 7.125 3 G P -5.495 -35.796 7.214 O3' -0.542 -34.173 8.841 4 A P -0.553 -32.565 8.905 O3' 4.133 -30.180 7.922 5 U P 3.882 -28.613 8.195 O3' 5.825 -25.411 4.187 6 A P 5.553 -23.834 4.369 O3' 7.361 -20.611 -0.601 7 U P 8.111 -19.270 -1.085 O3' 5.111 -16.942 -4.081 8 G P 4.350 -16.911 -5.501 O3' -0.292 -15.018 -5.389 9 G P 0.037 -13.442 -5.367 O3' -0.119 -9.813 -1.832 10 A P 0.758 -8.475 -1.661 O3' 0.487 -5.562 2.485 11 A P 1.582 -4.412 2.222 O3' 4.082 -2.318 6.694 12 G P 4.895 -1.048 6.125 O3' 9.643 0.048 8.765 13 A P 10.369 1.232 7.954 O3' 15.668 0.826 8.145 14 A P 16.209 2.150 7.404 O3' 20.366 2.287 4.201 15 C P 20.486 3.602 3.276 O3' 22.843 4.117 -1.223 16 C P 22.467 5.634 -1.615 O3' 20.689 5.956 -6.647 17 G P 20.132 7.404 -7.074 O3' 17.219 8.276 -11.491 18 G P 16.652 9.782 -11.540 O3' 12.028 11.040 -13.209 19 G P 11.678 12.610 -13.112 O3' 6.770 14.677 -12.335 20 G P 6.794 16.283 -12.444 O3' 6.603 19.748 -8.190 21 A P 7.215 21.203 -8.516 O3' 11.588 22.229 -4.712 22 A P 12.485 21.176 -3.887 O3' 11.272 18.137 0.998 23 A P 11.392 16.631 1.554 O3' 7.933 13.163 4.843 24 C P 8.492 11.655 4.828 O3' 4.148 8.670 2.975 25 U P 4.438 7.086 3.001 O3' 2.948 4.614 -1.394 26 U P 3.172 3.049 -1.094 O3' 4.197 0.422 -5.476 27 G P 4.475 -1.126 -5.129 O3' 8.500 -2.997 -8.052 28 G P 8.957 -4.506 -7.727 O3' 13.054 -7.066 -9.051 29 U P 12.806 -8.330 -8.083 O3' 16.397 -10.970 -5.337 30 U P 15.763 -11.976 -4.249 O3' 18.110 -13.343 0.277 31 C P 17.181 -14.389 1.075 O3' 16.571 -13.938 6.184 32 U P 15.775 -15.339 6.257 O3' 12.465 -14.221 10.587 33 U P 11.729 -15.601 10.963 O3' 6.913 -14.922 13.811 34 C P 5.679 -15.952 13.916 O3' 0.118 -16.029 12.078 35 C P -0.577 -17.472 12.248 O3' -5.347 -18.747 8.901 36 U P -5.819 -20.279 9.055 O3' -7.782 -22.653 4.019 37 A P -8.124 -24.055 3.305 O3' -5.529 -27.236 -1.141 38 A P -6.762 -28.061 -1.768 O3' -6.446 -28.408 -7.320 39 G P -5.664 -29.564 -8.123 O3' -0.296 -31.630 -8.758 40 U P -0.220 -33.237 -8.815 O3' 4.638 -35.377 -7.729 41 C P 4.463 -36.977 -7.666 O3' 7.339 -39.652 -4.016 42 C P 6.988 -41.225 -4.002 O3' 7.230 -43.396 0.802 43 U P 6.870 -44.962 0.906 O3' 3.822 -46.423 5.213 7 syn 1 43 W W c 2 42 + + c 3 41 + + c 4 40 - - c 5 39 W W c 6 36 H W t 8 35 + + c 9 34 + + c 10 33 - - c 11 32 - - c 12 31 + + c 13 30 - - c 14 29 - - c 15 28 + + c 16 27 + + c 16 28 W W c 17 26 W W c 18 25 W W c 19 24 + + c 20 23 S H t 37 38 S H c 1 43 5 8 35 13 SG1 6 7 SG2 21 22 SG3 36 38 1 14.338 550.000 2 13.686 532.677 3 13.034 515.354 4 12.382 498.031 5 11.731 480.708 6 11.079 463.385 7 9.776 428.739 8 7.821 376.771 9 7.169 359.448 10 6.517 342.125 11 5.865 324.802 12 5.214 307.479 13 4.562 290.156 14 3.910 272.833 15 3.259 255.510 16 2.607 238.187 17 1.955 220.864 18 1.303 203.541 19 0.652 186.218 20 0.000 168.896 21 7.265 144.698 22 32.512 143.748 23 41.575 167.331 24 42.227 184.654 25 42.878 201.977 26 43.530 219.300 27 44.182 236.623 28 44.834 253.946 29 45.485 271.269 30 46.137 288.592 31 46.789 305.915 32 47.440 323.238 33 48.092 340.561 34 48.744 357.884 35 49.396 375.207 36 50.047 392.530 37 50.699 409.852 38 52.002 444.498 39 53.306 479.144 40 53.958 496.467 41 54.609 513.790 42 55.261 531.113 43 55.913 548.436 6 21 W W t 8 22 S W t 8 23 S S t 21 6 W W t 21 36 W S c 22 8 W S t 23 8 S S t 9 24 ! ! ! 10 25 ! ! ! 23 35 ! ! ! 24 9 ! ! ! 24 10 ! ! ! 25 10 ! ! !