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| Title: | | 1.16A X-RAY STRUCTURE OF THE SYNTHETIC DNA FRAGMENT WITH THE INCORPORATED 2'-O-[(2-GUANIDINIUM)ETHYL]-5-METHYLURIDINE RESIDUES | |
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| Molecular Description: | 5'-D(GpCpGpTpAp(GMU)pApCpGpC)-3' |
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| Structural Features: | A DOUBLE HELIX |
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| Nucleic Acid Sequence: |
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| Chains | A,B: | | (DG) (DC) (DG) (DT) (DA) (GMU) (DA) (DC) (DG) (DC) |
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| Primary Citation: | Prakash, T.P., Lesnik, E., Mohan, V., Tereshko, V., Egli, M., Manoharan, M.
2'-O-[2-(Guanidinium)ethyl]-Modified Oligonucleotides: Stabilizing Effect on Duplex and Triplex Structures.
Org.Lett.
, 6,
pp. 1971 - 1974, 2004.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
P
21
21
21
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| Cell Constants: |
| a = 25.111 | b = 43.151 | c = 45.558 | (Ångstroms) |
 = 90.00 |  = 90.00 |  = 90.00 | (degrees) |
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| Refinement: | The structure was refined using the REFMAC 5.1.9999 program.
The R value is
13.2
for 16535 reflections
in the resolution range 20.00 to
1.16 Ångstroms
with Fobs > 0.00 sigma(Fobs).
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