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| Title: | | X-RAY STRUCTURE OF THE A-DECAMER GCGTATACGC WITH A SINGLE 2'-O-BUTYL THYMINE IN PLACE OF T6, MG-FORM | |
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| Molecular Description: | 5'-D(GpCpGpTpA)-R(p(2BT))-D(pApCpGpC)-3' |
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| Structural Features: | A DOUBLE HELIX |
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| Nucleic Acid Sequence: |
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| Chains | A,B: | | (DG) (DC) (DG) (DT) (DA) (2BT) (DA) (DC) (DG) (DC) |
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| Primary Citation: | Egli, M., Minasov, G., Tereshko, V., Pallan, P.S., Teplova, M., Inamati, G.B., Lesnik, E.A., Owens, S.R., Ross, B.S., Prakash, T.P., Manoharan, M.
Probing the influence of stereoelectronic effects on the biophysical properties of oligonucleotides: comprehensive analysis of the RNA affinity, nuclease resistance, and crystal structure of ten 2'-O-ribonucleic acid modifications.
Biochemistry
, 44,
pp. 9045 - 9057, 2005.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
P
41
21
2
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| Cell Constants: |
| a = 44.435 | b = 44.434 | c = 69.533 | (Ångstroms) |
 = 90.00 |  = 90.00 |  = 90.00 | (degrees) |
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| Refinement: | The structure was refined using the REFMAC 5.1.9999 program.
The R value is
23.7
for 3223 reflections
in the resolution range 20.00 to
2.30 Ångstroms
with I > 0. sigma(I).
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