 | | | |
| Title: | | CRYSTAL STRUCTURE OF THE A-DNA GCGTAT*CGC WITH A 2'-O-PROPARGYL THYMIDINE (T*) | |
|
| Molecular Description: | 5'-D(GpCpGpTpAp(2GT)pApCpGpC)-3' |
 |
| Structural Features: | A DOUBLE HELIX |
|
| Nucleic Acid Sequence: |
| | | |
| Chains | A,B: | | (DG) (DC) (DG) (DT) (DA) (2GT) (DA) (DC) (DG) (DC) |
|
|
| Primary Citation: | Egli, M., Minasov, G., Tereshko, V., Pallan, P.S., Teplova, M., Inamati, G.B., Lesnik, E.A., Owens, S.R., Ross, B.S., Prakash, T.P., Manoharan, M.
Probing the Influence of Stereoelectronic Effects on the Biophysical Properties of Oligonucleotides: Comprehensive Analysis of the RNA Affinity, Nuclease Resistance, and Crystal Structure of Ten 2'-O-Ribonucleic Acid Modifications.
Biochemistry
, 44,
pp. 9045 - 9057, 2005.
|
|
| | | |
| Experimental Information: | X-RAY DIFFRACTION |
|
| Space Group: |
P
21
21
21
|
|
| Cell Constants: |
| a = 24.831 | b = 44.983 | c = 45.409 | (Ångstroms) |
 = 90.00 |  = 90.00 |  = 90.00 | (degrees) |
|
|
| Refinement: | The structure was refined using the CNS program.
The R value is
16.3
for 7257 reflections
in the resolution range 20.0 to
1.55 Ångstroms
with Fobs > 0.0 sigma(Fobs).
|
|
|
