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| Title: |  | CRYSTAL AND MOLECULAR STRUCTURE OF THE ALTERNATING DODECAMER D(GCGTACGTACGC) IN THE A-DNA FORM: COMPARISON WITH THE ISOMORPHOUS NON-ALTERNATING DODECAMER D(CCGTACGTACGG) |  |
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| Molecular Description: | 5'-D(GpCpGpTpApCpGpTpApCpGpC)-3' |
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| Structural Features: | A DOUBLE HELIX |
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| Nucleic Acid Sequence: |
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| Chain | A: | |
(DG) (DC) (DG) (DT) (DA) (DC) (DG) (DT) (DA) (DC) (DG) (DC)
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| Primary Citation: | Bingman, C., Jain, S., Zon, G., Sundaralingam, M.
Crystal and molecular structure of the alternating dodecamer d(GCGTACGTACGC) in the A-DNA form: comparison with the isomorphous non-alternating dodecamer d(CCGTACGTACGG).
Nucleic Acids Res.
, 20,
pp. 6637 - 6647, 1992.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
P
61
2
2
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| Cell Constants: |
| a = 46.200 | b = 46.200 | c = 71.500 | (Ångstroms) |
= 90.00 | = 90.00 | = 120.00 | (degrees) |
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| Crystallization Conditions: |
| Method: | | VAPOR DIFFUSION |
| Drop: | | WATER, SPERMINE, [CO(NH3)6]3+, Na Cacodylate |
| Reservoir: | | WATER, PROPANOL |
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| Refinement: | The structure was refined using the NUCLSQ program.
The R value is
14.2
for 1089 reflections
in the resolution range 8.000 to
2.550 Ångstroms
with Fobs > 2.000 sigma(Fobs).
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