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| Title: | | HIGH-RESOLUTION CRYSTAL STRUCTURE OF A FULLY MODIFIED N3'-> P5' PHOSPHORAMIDATE DNA DODECAMER DUPLEX | |
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| Molecular Description: | 5'-D((C42)p(G38)p(C42)p(G38)p(A43)p
(A43)p(NYM)p(NYM)p(C42)p(G38)p(C42)p
DG)-3' |
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| Structural Features: | A DOUBLE HELIX, TWINNED CRYSTAL |
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| Nucleic Acid Sequence: |
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| Chains | A,B,C,D,E,F: | | (C42) (G38) (C42) (G38) (A43) (A43) (NYM) (NYM) (C42) (G38) (C42) (DG) |
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| Primary Citation: | Tereshko, V., Gryaznov, S., Egli, M.
Consequences of Replacing the DNA 3'-Oxygen by an Amino Group: High-Resolution Crystal Structure of a Fully Modified N3'--> P5' Phosphoramidate DNA Dodecamer Duplex
J.Am.Chem.Soc.
, 120,
pp. 269 - 283, 1998.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
H
3
2
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| Cell Constants: |
| a = 40.150 | b = 40.150 | c = 304.210 | (Ångstroms) |
 = 90.00 |  = 90.00 |  = 120.00 | (degrees) |
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| Refinement: | The structure was refined using the X-PLOR program.
The R value is
19.2
for 5854 reflections
in the resolution range 8.000 to
2.000 Ångstroms
with Fobs > 2.000 sigma(Fobs).
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