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| Title: | | DUPLEX [5'-D(GCGTA+TACGC)]2 WITH INCORPORATED 2'-O-ETHOXYMETHYLENE RIBONUCLEOSIDE | |
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| Molecular Description: | 5'-D(GpCpGpTpAp(T38)pApCpGpC)-3' |
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| Structural Features: | A DOUBLE HELIX |
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| Nucleic Acid Sequence: |
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| Chains | A, B: | |
(DG) (DC) (DG) (DT) (DA) (T38) (DA) (DC) (DG) (DC)
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| Primary Citation: | Tereshko, V., Portmann, S., Tay, E.C., Martin, P., Natt, F., Altmann, K.H., Egli, M.
Correlating structure and stability of DNA duplexes with incorporated 2'-O-modified RNA analogues.
Biochemistry
, 37,
pp. 10626 - 10634, 1998.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
P
21
21
21
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| Cell Constants: |
| a = 24.620 | b = 44.080 | c = 46.180 | (Ångstroms) |
 = 90.00 |  = 90.00 |  = 90.00 | (degrees) |
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| Crystallization Conditions: |
| Method: | | VAPOR DIFFUSION, HANGING DROP |
| Drop: | | SODIUM CACODYLATE, NaCl, BaCl2, SPERMINE, MPD |
| Reservoir: | | MPD |
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| Refinement: | The structure was refined using the X-PLOR 3.851 program.
The R value is
15.9
for 6414 reflections
in the resolution range 8.000 to
1.600 Ångstroms
with Fobs > 2.000 sigma(Fobs).
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