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| Title: | | 3'-DNA-RNA-5' JUNCTION FORMED DURING INITIATION OF MINUS-STRAND SYNTHESIS OF HIV REPLICATION | |
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| Molecular Description: | 5'-R(GpCpApGpUpGpGpC)-3'
5'-R(GpCpCpAP)-D(CpTpGpC)-3' |
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| Structural Features: | A DOUBLE HELIX |
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| Nucleic Acid Sequence: |
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| Chains | A,C: | | G C A G U G G C |
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| Primary Citation: | Mueller, U., Maier, G., Mochi Onori, A., Cellai, L., Heumann, H., Heinemann, U.
Crystal structure of an eight-base pair duplex containing the 3'-DNA-RNA-5' junction formed during initiation of minus-strand synthesis of HIV replication.
Biochemistry
, 37,
pp. 12005 - 12011, 1998.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
P
21
21
21
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| Cell Constants: |
| a = 42.740 | b = 44.150 | c = 51.930 | (Ångstroms) |
 = 90.00 |  = 90.00 |  = 90.00 | (degrees) |
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| Refinement: | The structure was refined using the X-PLOR program.
The R value is
22.0
for 7566 reflections
in the resolution range 15.000 to
1.940 Ångstroms
with Fobs > 0.000 sigma(Fobs).
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