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| Title: | | CRYSTAL STRUCTURE OF THE RRE HIGH AFFINITY SITE | |
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| Molecular Description: | 5'-R(ApApCpGpGpGpCpGpCpApGpApA)-3'
5'-R(UpCpUpGpApCpGpGp UpApCpGpUpUpU)-3' |
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| Structural Features: | A DOUBLE HELIX, FLIPPED-OUT BASES, OVERHANGING BASES |
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| Nucleic Acid Sequence: |
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| Chain | A: | | A A C G G G C G C A G A A |
| Chain | B: | | U C U G A C G G U A C G U U U |
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| Primary Citation: | Ippolito, J.A., Steitz, T.A.
The structure of the HIV-1 RRE high affinity rev binding site at 1.6 A resolution.
J.Mol.Biol.
, 295,
pp. 711 - 717, 2000.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
C
1
2
1
|
|
| Cell Constants: |
| a = 74.5 | b = 24.3 | c = 46.1 | (Ångstroms) |
 = 90. |  = 116.7 |  = 90. | (degrees) |
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| Refinement: | The structure was refined using the CNS program.
The R value is
21.1
for 9640 reflections
in the resolution range 15.0 to
1.60 Ångstroms
with Fobs > 0.0 sigma(Fobs).
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