 |  |  |  |
| Title: |  | CRYSTAL STRUCTURE OF THE REV BINDING ELEMENT OF HIV-1 |  |
 |
| Molecular Description: | REV BINDING ELEMENT |
 |
| Structural Features: | A DOUBLE HELIX, FLIPPED-OUT BASES |
 |
| Nucleic Acid Sequence: |
 |  |  |  |
| Chains | A,C,E,G: | | G C U G G G C G C A G G |
| Chains | B,D,F,H: | | C C U G A C G G U A C A G C |
|
 |
| Primary Citation: | Hung, L.W., Holbrook, E.L., Holbrook, S.R.
The crystal structure of the Rev binding element of HIV-1 reveals novel base pairing and conformational variability.
Proc.Natl.Acad.Sci.USA
, 97,
pp. 5107 - 5112, 2000.
|
 |
 |  |  |  |
| Experimental Information: | X-RAY DIFFRACTION |
 |
| Space Group: |
P
1
|
 |
| Cell Constants: |
| a = 23.993 | b = 53.930 | c = 64.729 | (Ångstroms) |
= 114.52 | = 89.88 | = 102.85 | (degrees) |
|
 |
| Refinement: | The structure was refined using the CNS 0.9 program.
The R value is
21.8
for 14136 reflections
in the resolution range 19.77 to
2.10 Ångstroms
with I > 1.0 sigma(I).
|
|
|