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| Title: | | MOLECULAR AND CRYSTAL STRUCTURE OF D(CGCGMO6AATCCGCG): THE WATSON-CRICK TYPE N6-METHOXYADENOSINE/CYTIDINE BASE-PAIRS IN B-DNA | |
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| Molecular Description: | 5'-D(CpGpCpGp(A47)pApTpCpCpGpCpG)-3' |
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| Structural Features: | B DOUBLE HELIX |
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| Nucleic Acid Sequence: |
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| Chains | A, B: | |
(DC) (DG) (DC) (DG) (A47) (DA) (DT) (DC) (DC) (DG) (DC) (DG)
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| Primary Citation: | Chatake, T., Ono, A., Ueno, Y., Matsuda, A., Takenaka, A.
Crystallographic studies on damaged DNAs. I. An N(6)-methoxyadenine residue forms a Watson-Crick pair with a cytosine residue in a B-DNA duplex.
J.Mol.Biol.
, 294,
pp. 1215 - 1222, 1999.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
P
21
21
21
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| Cell Constants: |
| a = 25.1 | b = 39.9 | c = 65.8 | (Ångstroms) |
 = 90.0 |  = 90.0 |  = 90.0 | (degrees) |
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| Crystallization Conditions: |
| Method: | | VAPOR DIFFUSION, HANGING DROP |
| Drop: | | MPD, SODIUM, CACODYLATE, MAGNESIUM ACETATE, SPERMINE |
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| Refinement: | The structure was refined using the X-PLOR 3.843 program.
The R value is
19.6
for 7676 reflections
in the resolution range 5.0 to
1.6 Ångstroms
with Fobs > 0.0 sigma(Fobs).
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