 | | | |
| Title: | | DNA MINOR-GROOVE RECOGNITION OF A TRIS-BENZIMIDAZOLE DRUG BY A NON-SELF-COMPLEMENTARY AT-RICH SEQUENCE | |
|
| Molecular Description: | 5'-D(CpGp(CBR)pApTpApTpTpTpGpCpG)-3'
5'-D(CpGpCpApApApTpApTpGpCpG)-3' |
 |
| Structural Features: | B DOUBLE HELIX |
|
| Nucleic Acid Sequence: |
| | | |
| Chain | A: | | (DC) (DG) (CBR) (DA) (DT) (DA) (DT) (DT) (DT) (DG) (DC) (DG) |
| Chain | B: | | (DC) (DG) (DC) (DA) (DA) (DA) (DT) (DA) (DT) (DG) (DC) (DG) |
|
|
| Primary Citation: | Aymami, J., Nunn, C.M., Neidle, S.
DNA minor groove recognition of a non-self-complementary AT-rich sequence by a tris-benzimidazole ligand.
Nucleic Acids Res.
, 27,
pp. 2691 - 2698, 1999.
|
|
| | | |
| Experimental Information: | X-RAY DIFFRACTION |
|
| Space Group: |
P
21
21
21
|
|
| Cell Constants: |
| a = 25.190 | b = 40.580 | c = 66.010 | (Ångstroms) |
 = 90.00 |  = 90.00 |  = 90.00 | (degrees) |
|
|
| Refinement: | The structure was refined using the SHELXL-97 program.
The R value is
20.7
for reflections
in the resolution range 8.0 to
2.3 Ångstroms
with Fobs > 4.0 sigma(Fobs).
|
|
|
