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| Title: | | CRYSTAL STRUCTURE OF TRIPLEX DNA | |
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| Molecular Description: | 5'-D(Cp(BRU)pCpCp(BRU)pCpCpGpCpGpCpG)-3'
5'-D(CpGpCpGpCp GpGpApG)-3' |
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| Structural Features: | B DOUBLE HELIX, BASE TRIPLET, FLIPPED-OUT BASES, OVERHANGING BASES |
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| Nucleic Acid Sequence: |
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| Chains | A, C: | |
(DC) (BRU) (DC) (DC) (BRU) (DC) (DC) (DG) (DC) (DG) (DC) (DG)
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| Chains | B, D: | |
(DC) (DG) (DC) (DG) (DC) (DG) (DG) (DA) (DG)
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| Primary Citation: | Rhee, S., Han, Z., Liu, K., Miles, H.T., Davies, D.R.
Structure of a triple helical DNA with a triplex-duplex junction.
Biochemistry
, 38,
pp. 16810 - 16815, 1999.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
P
42
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| Cell Constants: |
| a = 53.800 | b = 53.800 | c = 43.100 | (Ångstroms) |
 = 90.00 |  = 90.00 |  = 90.00 | (degrees) |
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| Crystallization Conditions: |
| Method: | | VAPOR DIFFUSION, HANGING DROP |
| Drop: | | NaCl, MgCl2, SPERMINE, MPD |
| Reservoir: | | MPD |
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| Refinement: | The structure was refined using the CNS program.
The R value is
21
for 21581 reflections
in the resolution range 20.00 to
1.80 Ångstroms
with Fobs > 4.000 sigma(Fobs).
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