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| Title: | | MOLECULAR AND CRYSTAL STRUCTURE OF D(CGCAAATTMO4CGCG): THE WATSON-CRICK TYPE N4-METHOXYCYTIDINE/ADENOSINE BASE PAIR IN B-DNA | |
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| Molecular Description: | 5'-D(CpGpCpApApApTpTp(C45)pGpCpG)-3' |
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| Structural Features: | B DOUBLE HELIX |
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| Nucleic Acid Sequence: |
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| Chains | A,B: | | (DC) (DG) (DC) (DA) (DA) (DA) (DT) (DT) (C45) (DG) (DC) (DG) |
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| Primary Citation: | Hossain, M.T., Sunami, T., Tsunoda, M., Hikima, T., Chatake, T., Ueno, Y., Matsuda, A., Takenaka, A.
Crystallographic studies on damaged DNAs IV. N(4)-methoxycytosine shows a second face for Watson-Crick base-pairing, leading to purine transition mutagenesis.
Nucleic Acids Res.
, 29,
pp. 3949 - 3954, 2001.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
P
21
21
21
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| Cell Constants: |
| a = 24.8 | b = 40.3 | c = 65.5 | (Ångstroms) |
 = 90.00 |  = 90.00 |  = 90.00 | (degrees) |
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| Refinement: | The structure was refined using the CNS 1.0 program.
The R value is
21.8
for reflections
in the resolution range 10.0 to
1.6 Ångstroms
with Fobs > 3.0 sigma(Fobs).
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