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| Title: | | CRYSTAL STRUCTURE OF A B-FORM DNA DUPLEX CONTAINING (L)-ALPHA-THREOFURANOSYL (3'-2') NUCLEOSIDES: A FOUR-CARBON SUGAR IS EASILY ACCOMMODATED INTO THE BACKBONE OF DNA | |
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| Molecular Description: | 5'-D(CpGpCpGpApAp(TFT)pTpCpGpCpG)-3' |
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| Structural Features: | B DOUBLE HELIX |
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| Nucleic Acid Sequence: |
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| Chains | A,B: | | (DC) (DG) (DC) (DG) (DA) (DA) (TFT) (DT) (DC) (DG) (DC) (DG) |
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| Primary Citation: | Wilds, C.J., Wawrzak, Z., Krishnamurthy, R., Eschenmoser, A., Egli, M.
Crystal Structure of a B-Form DNA Duplex Containing (L)-alpha-Threofuranosyl (3'-->2') Nucleosides: A Four-Carbon Sugar Is Easily Accommodated into the Backbone of DNA
J.Am.Chem.Soc.
, 124,
pp. 13716 - 13721, 2002.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
P
21
21
21
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| Cell Constants: |
| a = 25.277 | b = 40.080 | c = 65.860 | (Ångstroms) |
 = 90.00 |  = 90.00 |  = 90.00 | (degrees) |
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| Refinement: | The structure was refined using the SHELXL-97 program.
The R value is
16.0
for 21311 reflections
in the resolution range 20. to
1.20 Ångstroms
. |
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