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| Title: | | 5'-D(*CP*GP*CP*(HYD)AP*AP*AP*TP*TP*TP*GP*CP*G)-3', 2'-(4-ETHOXYPHENYL)-5-(4-METHYL-1-PIPERAZINYL)-2,5'-BI-BENZIMIDAZOLE | |
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| Molecular Description: | 5'-D(CpGpCp(IGU)pApApTpTpTpGpCpG)-3'
2'-(4-ETHOXYPHENYL)-5-(4-METHYL-1-PIPERAZINYL)-2,5'-BI-BENZIMIDAZOLE |
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| Structural Features: | B DOUBLE HELIX |
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| Nucleic Acid Sequence: |
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| Chains | A, B: | |
(DC) (DG) (DC) (IGU) (DA) (DA) (DT) (DT) (DT) (DG) (DC) (DG)
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| Primary Citation: | Robinson, H., Gao, Y.G., Bauer, C., Roberts, C., Switzer, C., Wang, A.H.
2'-Deoxyisoguanosine adopts more than one tautomer to form base pairs with thymidine observed by high-resolution crystal structure analysis.
Biochemistry
, 37,
pp. 10897 - 10905, 1998.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
P
21
21
21
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| Cell Constants: |
| a = 25.759 | b = 41.084 | c = 64.307 | (Ångstroms) |
 = 90.00 |  = 90.00 |  = 90.00 | (degrees) |
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| Crystallization Conditions: |
| Method: | | VAPOR DIFFUSION |
| Drop: | | WATER, MgCl2, SPERMINE, SODIUM CACODYLATE |
| Reservoir: | | WATER, MPD |
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| Refinement: | The structure was refined using the SHELXL-97 program.
The R value is
24.5
for 11253 reflections
in the resolution range 10.000 to
1.400 Ångstroms
with Fobs > 0.000 sigma(Fobs).
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