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| Title: | | STRUCTURAL BASIS FOR RECOGNITION OF A-T AND T-A BASE PAIRS IN THE MINOR GROOVE OF B-DNA | |
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| Molecular Description: | 5'-D(CpCpApGpTpApCpTpGpG)-3'
IMIDAZOLE-PYRROLE POLYAMIDE |
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| Structural Features: | B DOUBLE HELIX |
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| Nucleic Acid Sequence: |
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| Chains | A, B: | |
(DC) (DC) (DA) (DG) (DT) (DA) (DC) (DT) (DG) (DG)
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| Primary Citation: | Kielkopf, C.L., White, S., Szewczyk, J.W., Turner, J.M., Baird, E.E., Dervan, P.B., Rees, D.C.
A structural basis for recognition of A.T and T.A base pairs in the minor groove of B-DNA.
Science
, 282,
pp. 111 - 115, 1998.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
C
1
2
1
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| Cell Constants: |
| a = 60.660 | b = 30.200 | c = 43.460 | (Ångstroms) |
 = 90.00 |  = 123.59 |  = 90.00 | (degrees) |
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| Crystallization Conditions: |
| Method: | | VAPOR DIFFUSION, HANGING DROP |
| Drop: | | CALCIUM ACETATE, MPD, TRIS |
| Reservoir: | | CALCIUM ACETATE, MPD, TRIS |
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| Refinement: | The structure was refined using the X-PLOR 3.1 program.
The R value is
21.9
for 3402 reflections
in the resolution range 20.000 to
2.100 Ångstroms
with Fobs > 0.000 sigma(Fobs).
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