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| Title: |  | THE STRUCTURE OF B-HELICAL C-G-A-T-C-G-A-T-C-G AND COMPARISON WITH C-C-A-A-C-G-T-T-G-G. THE EFFECT OF BASE PAIR REVERSALS |  |
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| Molecular Description: | 5'-D(CpGpApTpCpGpApTpCpG)-3' |
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| Structural Features: | B DOUBLE HELIX |
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| Nucleic Acid Sequence: |
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| Chains | A, B: | |
(DC) (DG) (DA) (DT) (DC) (DG) (DA) (DT) (DC) (DG)
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| Primary Citation: | Grzeskowiak, K., Yanagi, K., Prive, G.G., Dickerson, R.E.
The structure of B-helical C-G-A-T-C-G-A-T-C-G and comparison with C-C-A-A-C-G-T-T-G-G. The effect of base pair reversals.
J.Biol.Chem.
, 266,
pp. 8861 - 8883, 1991.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
P
21
21
21
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| Cell Constants: |
| a = 38.930 | b = 39.630 | c = 33.300 | (Ångstroms) |
= 90.00 | = 90.00 | = 90.00 | (degrees) |
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| Crystallization Conditions: |
| Method: | | VAPOR DIFFUSION, SITTING DROP |
| Drop: | | WATER, MPD, MgCl2 |
| Reservoir: | | WATER, MPD |
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| Refinement: | The structure was refined using the NUCLSQ program.
The R value is
16.1
for 5107 reflections
in the resolution range 8.000 to
1.500 Ångstroms
with Fobs > 2.000 sigma(Fobs).
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