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| Title: | | CRYSTAL STRUCTURE AND SEQUENCE-DEPENDENT CONFORMATION OF THE A.G MIS-PAIRED OLIGONUCLEOTIDE D(CGCAAGCTGGCG) | |
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| Molecular Description: | 5'-D(CpGpCpApApGpCpTpGpGpCpG)-3' |
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| Structural Features: | B DOUBLE HELIX |
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| Nucleic Acid Sequence: |
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| Chains | A, B: | |
(DC) (DG) (DC) (DA) (DA) (DG) (DC) (DT) (DG) (DG) (DC) (DG)
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| Primary Citation: | Webster, G.D., Sanderson, M.R., Skelly, J.V., Neidle, S., Swann, P.F., Li, B.F., Tickle, I.J.
Crystal structure and sequence-dependent conformation of the A.G mispaired oligonucleotide d(CGCAAGCTGGCG).
Proc.Natl.Acad.Sci.USA
, 87,
pp. 6693 - 6697, 1990.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
P
21
21
21
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| Cell Constants: |
| a = 25.290 | b = 41.780 | c = 64.760 | (Ångstroms) |
 = 90.00 |  = 90.00 |  = 90.00 | (degrees) |
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| Crystallization Conditions: |
| Method: | | VAPOR DIFFUSION |
| Drop: | | WATER, MPD, MgCl2, SPERMINE |
| Reservoir: | | WATER, MPD |
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| Refinement: | The structure was refined using the NUCLSQ program.
The R value is
19.3
for 1710 reflections
in the resolution of 2.500
with Fobs > 3.000 sigma(Fobs).
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