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| Title: | | METHYLATION OF THE ECORI RECOGNITION SITE DOES NOT ALTER DNA CONFORMATION. THE CRYSTAL STRUCTURE OF D(CGCGAM6ATTCGCG) AT 2.0 ANGSTROMS RESOLUTION | |
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| Molecular Description: | 5'-D(CpGpCpGpAp(6MA)pTpTpCpGpCpG)-3' |
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| Structural Features: | B DOUBLE HELIX |
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| Nucleic Acid Sequence: |
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| Chains | A,B: | | (DC) (DG) (DC) (DG) (DA) (6MA) (DT) (DT) (DC) (DG) (DC) (DG) |
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| Primary Citation: | Frederick, C.A., Quigley, G.J., van der Marel, G.A., van Boom, J.H., Wang, A.H., Rich, A.
Methylation of the EcoRI recognition site does not alter DNA conformation: the crystal structure of d(CGCGAm6ATTCGCG) at 2.0-A resolution.
J.Biol.Chem.
, 263,
pp. 17872 - 17879, 1988.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
P
21
21
21
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| Cell Constants: |
| a = 25.620 | b = 40.390 | c = 67.320 | (Ångstroms) |
 = 90.00 |  = 90.00 |  = 90.00 | (degrees) |
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| Refinement: | The structure was refined using the NUCLSQ program.
The R value is
16.9
for 2379 reflections
in the resolution of 2.000
with Fobs > 2.000 sigma(Fobs).
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