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| Title: | | HIGH-RESOLUTION STRUCTURE OF A MUTAGENIC LESION IN DNA | |
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| Molecular Description: | 5'-D(CpGpCp(6OG)pApApTpTpTpGpCpG)-3' |
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| Structural Features: | B DOUBLE HELIX |
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| Nucleic Acid Sequence: |
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| Chains | A, B: | |
(DC) (DG) (DC) (6OG) (DA) (DA) (DT) (DT) (DT) (DG) (DC) (DG)
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| Primary Citation: | Leonard, G.A., Thomson, J., Watson, W.P., Brown, T.
High-resolution structure of a mutagenic lesion in DNA.
Proc.Natl.Acad.Sci.USA
, 87,
pp. 9573 - 9576, 1990.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
P
21
21
21
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| Cell Constants: |
| a = 25.440 | b = 40.700 | c = 65.990 | (Ångstroms) |
 = 90.00 |  = 90.00 |  = 90.00 | (degrees) |
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| Crystallization Conditions: |
| Method: | | VAPOR DIFFUSION |
| Drop: | | WATER, HEXYLENE GLYCOL, MgCl2, SPERMINE, Na Cacodylate |
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| Refinement: | The structure was refined using the NUCLSQ program.
The R value is
18.5
for 3118 reflections
in the resolution range 7.000 to
2.000 Ångstroms
with Fobs > 3.000 sigma(Fobs).
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