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| Title: | | CONFORMATION OF THE GUANINE.8-OXOADENINE BASE PAIRS IN THE CRYSTAL STRUCTURE OF D(CGCGAATT(O8A)GCG) | |
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| Molecular Description: | 5'-D(CpGpCpGpApApTpTp(A38)pGpCpG)-3' |
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| Structural Features: | B DOUBLE HELIX |
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| Nucleic Acid Sequence: |
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| Chains | A, B: | |
(DC) (DG) (DC) (DG) (DA) (DA) (DT) (DT) (A38) (DG) (DC) (DG)
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| Primary Citation: | Leonard, G.A., Guy, A., Brown, T., Teoule, R., Hunter, W.N.
Conformation of guanine-8-oxoadenine base pairs in the crystal structure of d(CGCGAATT(O8A)GCG).
Biochemistry
, 31,
pp. 8415 - 8420, 1992.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
P
21
21
21
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| Cell Constants: |
| a = 25.480 | b = 41.840 | c = 64.910 | (Ångstroms) |
 = 90.00 |  = 90.00 |  = 90.00 | (degrees) |
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| Crystallization Conditions: |
| Method: | | VAPOR DIFFUSION, SITTING DROP |
| Drop: | | WATER, MPD, Na Cacodylate, Mg ACETATE, SPERMINE |
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| Refinement: | The structure was refined using the NUCLSQ program.
The R value is
15.1
for 1119 reflections
in the resolution range 7.000 to
2.800 Ångstroms
with Fobs > 2.000 sigma(Fobs).
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