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| Title: | | CRYSTAL STRUCTURE OF A DNA DUPLEX CONTAINING 8-HYDROXYDEOXYGUANINE.ADENINE BASE-PAIRS | |
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| Molecular Description: | 5'-D(CpGpCpApApApTpTp(8OG)pGpCpG)-3' |
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| Structural Features: | B DOUBLE HELIX |
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| Nucleic Acid Sequence: |
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| Chains | A,B: | | (DC) (DG) (DC) (DA) (DA) (DA) (DT) (DT) (8OG) (DG) (DC) (DG) |
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| Primary Citation: | McAuley-Hecht, K.E., Leonard, G.A., Gibson, N.J., Thomson, J.B., Watson, W.P., Hunter, W.N., Brown, T.
Crystal structure of a DNA duplex containing 8-hydroxydeoxyguanine-adenine base pairs.
Biochemistry
, 33,
pp. 10266 - 10270, 1994.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
P
21
21
21
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| Cell Constants: |
| a = 24.670 | b = 40.490 | c = 65.140 | (Ångstroms) |
 = 90.00 |  = 90.00 |  = 90.00 | (degrees) |
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| Refinement: | The structure was refined using the NUCLSQ program.
The R value is
16.8
for 1843 reflections
in the resolution range 10.000 to
2.500 Ångstroms
with Fobs > 2.000 sigma(Fobs).
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