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| Title: | | CRYSTAL STRUCTURE OF B-DNA WITH INCORPORATED 2'-DEOXY-2'-FLUORO-ARABINO-FURANOSYL THYMINES: IMPLICATIONS OF CONFORMATIONAL PREORGANIZATION FOR DUPLEX STABILITY | |
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| Molecular Description: | 5'-D(CpGpCpGpApAp(TAF)pTpCpGpCpG)-3' |
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| Structural Features: | B DOUBLE HELIX |
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| Nucleic Acid Sequence: |
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| Chains | A,B: | | (DC) (DG) (DC) (DG) (DA) (DA) (TAF) (DT) (DC) (DG) (DC) (DG) |
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| Primary Citation: | Berger, I., Tereshko, V., Ikeda, H., Marquez, V.E., Egli, M.
Crystal structures of B-DNA with incorporated 2'-deoxy-2'-fluoro-arabino-furanosyl thymines: implications of conformational preorganization for duplex stability.
Nucleic Acids Res.
, 26,
pp. 2473 - 2480, 1998.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
P
21
21
21
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| Cell Constants: |
| a = 25.200 | b = 39.710 | c = 65.680 | (Ångstroms) |
 = 90.00 |  = 90.00 |  = 90.00 | (degrees) |
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| Refinement: | The structure was refined using the X-PLOR 3.851 program.
The R value is
21.8
for 8507 reflections
in the resolution range 8.000 to
1.550 Ångstroms
with Fobs > 2.000 sigma(Fobs).
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