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| Title: | | THE CRYSTAL STRUCTURE ANALYSIS OF D(CGCGAASSCGCG)2: A SYNTHETIC DNA DODECAMER DUPLEX CONTAINING FOUR 4'-THIO-2'-DEOXYTHYMIDINE NUCLEOTIDES | |
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| Molecular Description: | 5'-D(CpGpCpGpApAp)-D((T49)p(T49)p)-D(Cp
GpCpG)-3' |
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| Structural Features: | B DOUBLE HELIX |
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| Nucleic Acid Sequence: |
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| Chains | A,B: | | (DC) (DG) (DC) (DG) (DA) (DA) (T49) (T49) (DC) (DG) (DC) (DG) |
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| Primary Citation: | Boggon, T.J., Hancox, E.L., McAuley-Hecht, K.E., Connolly, B.A., Hunter, W.N., Brown, T., Walker, R.T., Leonard, G.A.
The crystal structure analysis of d(CGCGAASSCGCG)2, a synthetic DNA dodecamer duplex containing four 4'-thio-2'-deoxythymidine nucleotides.
Nucleic Acids Res.
, 24,
pp. 951 - 961, 1996.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
P
21
21
21
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| Cell Constants: |
| a = 24.993 | b = 40.364 | c = 65.993 | (Ångstroms) |
 = 90.00 |  = 90.00 |  = 90.00 | (degrees) |
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| Refinement: | The structure was refined using the X-PLOR program.
The R value is
20.1
for 2605 reflections
in the resolution range 8.000 to
2.400 Ångstroms
with Fobs > 2.000 sigma(Fobs).
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