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| Title: | | CRYSTAL STRUCTURE OF EPIDOXORUBICIN-FORMALDEHYDE VIRTUAL CROSSLINK OF DNA | |
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| Molecular Description: | 5'-D(CpGpCp(G49)pCpG)-3'
DOXORUBICIN |
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| Structural Features: | RH DOUBLE HELIX |
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| Nucleic Acid Sequence: |
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| Chain | A: | | (DC) (DG) (DC) (G49) (DC) (DG) |
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| Primary Citation: | Podell, E.R., Harrington, D.J., Taatjes, D.J., Koch, T.H.
Crystal structure of epidoxorubicin-formaldehyde virtual crosslink of DNA and evidence for its formation in human breast-cancer cells.
Acta Crystallogr.,Sect.D
, 55,
pp. 1516 - 1523, 1999.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
P
41
21
2
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| Cell Constants: |
| a = 28.110 | b = 28.110 | c = 52.540 | (Ångstroms) |
 = 90.00 |  = 90.00 |  = 90.00 | (degrees) |
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| Refinement: | The structure was refined using the CNS program.
The R value is
20.5
for 2612 reflections
in the resolution range 30.0 to
1.6 Ångstroms
with I > 2.0 sigma(I).
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