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| Title: | | BINDING OF A MACROCYCLIC BISACRIDINE AND AMETANTRONE TO CGTACG INVOLVES SIMILAR UNUSUAL INTERCALATION PLATFORMS (AMETANTRONE COMPLEX) | |
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| Molecular Description: | DNA (5'-D(CpGpTpApCp
G)-3') - ANTHRACENE-9-10-DIOL COMPLEX |
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| Structural Features: | B DOUBLE HELIX, flipped-out bases, stacked anthracene molecule |
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| Nucleic Acid Sequence: |
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| Chains | A,B: | | (DC) (DG) (DT) (DA) (DC) (DG) |
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| Primary Citation: | Yang, X.L., Robinson, H., Gao, Y.G., Wang, A.H.
Binding of a macrocyclic bisacridine and ametantrone to CGTACG involves similar unusual intercalation platforms.
Biochemistry
, 39,
pp. 10950 - 10957, 2000.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
C
2
2
2
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| Cell Constants: |
| a = 29.094 | b = 52.714 | c = 40.183 | (Ångstroms) |
 = 90.00 |  = 90.00 |  = 90.00 | (degrees) |
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| Refinement: | The structure was refined using the SHELXL-97 program.
The R value is
24.9
for 3272 reflections
in the resolution range 20. to
1.6 Ångstroms
with I > 2. sigma(I).
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