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| Title: | | CYCLO-BUTYL-BIS-FURAMIDINE COMPLEXED WITH DCGCGAATTCGCG | |
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| Molecular Description: | 5'-d(CpGpCpGpApApTpTpCpGpCpG)-3'
BIS-PHENYL FURAN DERIVATIVE |
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| Structural Features: | B DOUBLE HELIX |
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| Nucleic Acid Sequence: |
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| Chains | A,B: | | (DC) (DG) (DC) (DG) (DA) (DA) (DT) (DT) (DC) (DG) (DC) (DG) |
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| Primary Citation: | Simpson, I.J., Lee, M., Kumar, A., Boykin, D.W., Neidle, S.
DNA minor groove interactions and the biological activity of 2,5-bis-[4-(N-alkylamidino)phenyl] furans
Bioorg.Med.Chem.Lett.
, 10,
pp. 2593 - 2597, 2000.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
P
21
21
21
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| Cell Constants: |
| a = 24.86 | b = 40.71 | c = 66.44 | (Ångstroms) |
 = 90. |  = 90. |  = 90. | (degrees) |
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| Refinement: | The structure was refined using the SHELXL-97 program.
The R value is
18.8
for 4992 reflections
in the resolution range 8. to
2. Ångstroms
with Fobs > 2. sigma(Fobs).
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