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| Title: | | 5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3'-SYMMETRIC BIS-BENZIMIDAZOLE COMPLEX | |
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| Molecular Description: | 5'-D(CpGpCpGpApApTpTpCpGpCpG)-3'
BENZIMIDAZOLE DERIVATIVE |
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| Structural Features: | B DOUBLE HELIX |
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| Nucleic Acid Sequence: |
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| Chains | A,B: | | (DC) (DG) (DC) (DG) (DA) (DA) (DT) (DT) (DC) (DG) (DC) (DG) |
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| Primary Citation: | Mann, J., Baron, A., Opoku-Boahen, Y., Johansson, E., Parkinson, G., Kelland, L.R., Neidle, S.
A new class of symmetric bisbenzimidazole-based DNA minor groove-binding agents showing antitumor activity.
J.Med.Chem.
, 44,
pp. 138 - 144, 2001.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
P
21
21
21
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| Cell Constants: |
| a = 25.15 | b = 39.94 | c = 65.65 | (Ångstroms) |
 = 90.00 |  = 90.00 |  = 90.00 | (degrees) |
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| Refinement: | The structure was refined using the SHELXL-97 program.
The R value is
24.4
for 4063 reflections
in the resolution range 8. to
2. Ångstroms
with Fobs > 4. sigma(Fobs).
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