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| Title: | | INTERCALATION OF AN 9ACRIDINE-PEPTIDE DRUG IN A DNA DODECAMER | |
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| Molecular Description: | 5'-D(CpGpCpGpApApTpTpCpGpCpG)-3'
ACRIDINE-PEPTIDE DRUG |
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| Structural Features: | B DOUBLE HELIX |
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| Nucleic Acid Sequence: |
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| Chains | A,B,C,D,E,F,G,H,I,J,K,L: | | (DC) (DG) (DC) (DG) (DA) (DA) (DT) (DT) (DC) (DG) (DC) (DG) |
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| Protein Sequence: |
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| Primary Citation: | Malinina, L., Soler-Lopez, M., Aymami, J., Subirana, J.A.
Intercalation of an acridine-peptide drug in an AA/TT base step in the crystal structure of [d(CGCGAATTCGCG)](2) with six duplexes and seven Mg(2+) ions in the asymmetric unit.
Biochemistry
, 41,
pp. 9341 - 9348, 2002.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
P
21
21
21
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| Cell Constants: |
| a = 66.471 | b = 68.365 | c = 77.362 | (Ångstroms) |
 = 90.00 |  = 90.00 |  = 90.00 | (degrees) |
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| Refinement: | The structure was refined using the REFMAC 5 program.
The R value is
22.0
for 8086 reflections
in the resolution range 20.00 to
2.700 Ångstroms
. |
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