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| Title: | | 2.4 ANGSTROM CRYSTAL STRUCTURE OF AN OXALIPLATIN 1,2-D(GPG) INTRASTRAND CROSS-LINK IN A DNA DODECAMER DUPLEX | |
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| Molecular Description: | 5'-D(CpCpTpCpTpGpGpTpCpTpCpC)-3'
OXALIPLATIN |
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| Structural Features: | B DOUBLE HELIX |
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| Nucleic Acid Sequence: |
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| Chain | A: | | (DC) (DC) (DT) (DC) (DT) (DG) (DG) (DT) (DC) (DT) (DC) (DC) |
| Chain | B: | | (DG) (DG) (DA) (DG) (DA) (DC) (DC) (DA) (DG) (DA) (DG) (DG) |
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| Primary Citation: | Spingler, B., Whittington, D.A., Lippard, S.J.
2.4 A crystal structure of an oxaliplatin 1,2-d(GpG) intrastrand cross-link in a DNA dodecamer duplex.
Inorg.Chem.
, 40,
pp. 5596 - 5602, 2001.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
I
2
2
2
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| Cell Constants: |
| a = 41.942 | b = 51.246 | c = 87.049 | (Ångstroms) |
 = 90.00 |  = 90.00 |  = 90.00 | (degrees) |
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| Refinement: | The structure was refined using the SHELXL-97 program.
The R value is
23.0
for 4935 reflections
in the resolution range 100. to
2.40 Ångstroms
with Fobs > 4.0 sigma(Fobs).
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