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| Title: |  | 1.6A RESOLUTION CRYSTAL STRUCTURES OF THE DNA OCTAMERS D(IUATATAC) AND D(ITITACAC):BINDING OF TWO DISTAMYCIN DRUGS SIDE-BY-SIDE |  |
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| Molecular Description: | 5'-D(IpTpIpTpApCpApC)-3' DISTAMYCIN A |
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| Structural Features: | B DOUBLE HELIX |
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| Nucleic Acid Sequence: |
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| Chain | A: | | (DI) (DT) (DI) (DT) (DA) (DC) (DA) (DC) |
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| Primary Citation: | Deng, J., Pan, B., Sundaralingam, M.
Structure of d(ITITACAC) complexed with distamycin at 1.6 A resolution.
Acta Crystallogr.,Sect.D
, 59,
pp. 2342 - 2344, 2003.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
C
1
2
1
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| Cell Constants: |
| a = 33.260 | b = 25.050 | c = 28.300 | (Ångstroms) |
= 90.00 | = 124.23 | = 90.00 | (degrees) |
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| Refinement: | The structure was refined using the CNS program.
The R value is
14.9
for 2468 reflections
in the resolution range 10. to
1.6 Ångstroms
with Fobs > 2. sigma(Fobs).
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