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| Title: | | CRYSTAL STRUCTURE OF THE QUADRUPLEX DNA-DRUG COMPLEX | |
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| Molecular Description: | 5'-D(GpGpGpGpTpTpTpTpGpGpGpG)-3'
acridine derivative |
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| Structural Features: | QUADRUPLE HELIX, LOOP |
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| Nucleic Acid Sequence: |
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| Chains | A, B: | |
(DG) (DG) (DG) (DG) (DT) (DT) (DT) (DT) (DG) (DG) (DG) (DG)
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| Primary Citation: | Haider, S.M., Parkinson, G.N., Neidle, S.
Structure of a G-quadruplex-Ligand Complex
J.Mol.Biol.
, 326,
pp. 117 - 125, 2003.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
P
21
21
2
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| Cell Constants: |
| a = 55.451 | b = 42.736 | c = 26.926 | (Ångstroms) |
 = 90.00 |  = 90.00 |  = 90.00 | (degrees) |
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| Refinement: | The structure was refined using the SHELXL-97 program.
The R value is
13.94
for 6932 reflections
in the resolution range 10 to
1.75 Ångstroms
with Fobs > 0 sigma(Fobs).
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