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| Title: | | ATOMIC RESOLUTION STRUCTURE OF 5BR-9AMINO-DACA WITH D[CGTACG]2 | |
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| Molecular Description: | 5'-D(CpGpTpApCpG)-3'
5-BROMO-N[2-(DIMETHYLAMINO)ETHYL]-9-AMINOACRIDINE-4-CARBOXAMIDE |
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| Structural Features: | B DOUBLE HELIX |
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| Nucleic Acid Sequence: |
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| Chain | A: | | (DC) (DG) (DT) (DA) (DC) (DG) |
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| Primary Citation: | Teixeira, S.C.M., Thorpe, J.H., Todd, A.K., Cardin, C.J.
Heavy Going: the Atomic Resolution Structure of a Topoisomerase II Poison Intercalating into DNA in Multiple Orientations Also Reveals a Multiple Adenine-Thymine Hydrogen Bonding Pattern
To be Published |
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
P
64
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| Cell Constants: |
| a = 30.186 | b = 30.186 | c = 39.443 | (Ångstroms) |
 = 90.00 |  = 90.00 |  = 120.00 | (degrees) |
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| Refinement: | The structure was refined using the SHELXL-97 program.
The R value is
15.7
for 7350 reflections
in the resolution range 10.00 to
1.10 Ångstroms
with Fobs > 4.0 sigma(Fobs).
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