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| Title: |  | ACTINOMYCIN D BINDING TO ATGCTGCAT |  |
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| Molecular Description: | 5'-D(ApTpGpCpTpGpCpApT)-3' ACTINOMYCIN D |
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| Structural Features: | B DOUBLE HELIX |
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| Nucleic Acid Sequence: |
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| Chains | A,B: | | (DA) (DT) (DG) (DC) (DT) (DG) (DC) (DA) (DT) |
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| Protein Sequence: |
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| Primary Citation: | Hou, M.-H., Robinson, H., Gao, Y.-G., Wang, A.H.-J.
Crystal Structure of Actinomycin D Bound to the CTG Triplet Repeat Sequences Linked to Neurological Diseases
Nucleic Acids Res.
, 30,
pp. 4910 - 4917, 2002.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
P
31
1
2
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| Cell Constants: |
| a = 47.24 | b = 47.24 | c = 69.45 | (Ångstroms) |
= 90. | = 90. | = 120. | (degrees) |
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| Refinement: | The structure was refined using the X-PLOR program.
The R value is
23.3
for 2650 reflections
in the resolution range 20. to
2.6 Ångstroms
with I > 5. sigma(I).
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