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| Title: | | STRUCTURE OF ELLIPTICINE IN COMPLEX WITH A 6-BP DNA | |
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| Molecular Description: | 5'-D(CpGpApTpCpG)-3'
ELLIPTICINE |
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| Structural Features: | B DOUBLE HELIX |
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| Nucleic Acid Sequence: |
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| Chains | A,B: | | (DC) (DG) (DA) (DT) (DC) (DG) |
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| Primary Citation: | Canals, A., Purciolas, M., Aymami, J., Coll, M.
The anticancer agent ellipticine unwinds DNA by intercalative binding in an orientation parallel to base pairs.
Acta Crystallogr.,Sect.D
, 61,
pp. 1009 - 1012, 2005.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
P
65
|
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| Cell Constants: |
| a = 24.860 | b = 24.860 | c = 78.860 | (Ångstroms) |
 = 90.00 |  = 90.00 |  = 120.00 | (degrees) |
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| Refinement: | The structure was refined using the REFMAC 5.2.0005 program.
The R value is
22.0
for 4197 reflections
in the resolution range 16.66 to
1.50 Ångstroms
with Fobs > 0.0 sigma(Fobs).
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