NDB ID: DD0091
Title: STRUCTURAL ADAPTATION AND CONSERVATION IN QUADRUPLEX-DRUG RECOGNITION Molecular Description: 5'-D(DTpDApDGpDGpDGpDTpDTpDApDGpDGpDGp DT)-3' Structural Features: QUADRUPLE HELIX, LOOP Nucleic Acid Sequence: Chain A: (DT) (DA) (DG) (DG) (DG) (DT) (DT) (DA) (DG) (DG) (DG) (DT) Primary Citation: Parkinson, G.N., Cuenca, F., Neidle, S. Topology conservation and loop flexibility in quadruplex-drug recognition: crystal structures of inter- and intramolecular telomeric DNA quadruplex-drug complexes J.Mol.Biol. , 381, pp. 1145 - 1156, 2008. Experimental Information: X-RAY DIFFRACTION Space Group: P  64   2  2 Cell Constants: a = 61.350 b = 61.350 c = 43.630 (Ångstroms) = 90.00 = 90.00 = 120.00 (degrees) Refinement: The structure was refined using the REFMAC 5.1.24 program. The R value is 25.4 for 2520 reflections in the resolution range 10.00 to 2.20 Ångstroms with Fobs > 0.0 sigma(Fobs).	Biological Assembly 1 Other Views Asymmetric Unit Crystal Packing Enlarge Biological Assembly 1
Coordinate + Structure Data Asymmetric Unit coordinates (pdb format, Unix compressed(.gz)) Asymmetric Unit coordinates (cif format, Unix compressed(.gz)) Biological Assembly coordinates (pdb format) Structure Factors (cif format) XML | Complete with coordinates (xml format, GNU compressed(.gz)) XML | Coordinates only (xml format, GNU compressed(.gz)) XML | Header only (xml format, GNU compressed(.gz))	Derivative Data Nucleic Acid Backbone Torsions Base Pair Parameters Base Pair Step Parameters Hydrogen Bonding Classification
Links
The RCSB Protein Data Bank: 3CCO
PubMed: 18619463
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