 | | | |
| Title: | | A BIMOLECULAR ANTI-PARALLEL-STRANDED OXYTRICHA NOVA TELOMERIC QUADRUPLEX IN COMPLEX WITH A 3,6-DISUBSTITUTED ACRIDINE BSU-6042 IN A LARGE UNIT CELL | |
|
| Molecular Description: | 5'-D(DGpDGpDGpDGpDTpDTpDTpDTpDGpDGpDGp
DG)-3' |
 |
| Structural Features: | QUADRUPLE HELIX, LOOP, TETRAPLEX |
|
| Nucleic Acid Sequence: |
| | | |
| Chains | A,B,C,D: | | (DG) (DG) (DG) (DG) (DT) (DT) (DT) (DT) (DG) (DG) (DG) (DG) |
|
|
| Primary Citation: | Campbell, N.H., Patel, M., Tofa, A.B., Ghosh, R., Parkinson, G.N., Neidle, S.
Selectivity in Ligand Recognition of G-Quadruplex Loops.
Biochemistry
, 48,
pp. 1675 - 1680, 2009.
|
|
| | | |
| Experimental Information: | X-RAY DIFFRACTION |
|
| Space Group: |
P
21
21
21
|
|
| Cell Constants: |
| a = 55.356 | b = 42.542 | c = 48.636 | (Ångstroms) |
 = 90.00 |  = 90.00 |  = 90.00 | (degrees) |
|
|
| Refinement: | The structure was refined using the REFMAC 5.2.0019 program.
The R value is
23.4
for 5575 reflections
in the resolution range 27.68 to
2.20 Ångstroms
. |
|
|
