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| Title: | | STRUCTURE OF A NOVEL DRUG-NUCLEIC ACID CRYSTALLINE COMPLEX: 1,10-PHENANTHROLINE-PLATINUM(II) ETHYLENEDIAMINE-5'-PHOSPHORYL-THYMIDYLYL(3'-5') DEOXYADENOSINE | |
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| Molecular Description: | 5'-D(pTpA)-3'
1,10-PHENANTHROLINE-PLATINUM(II) |
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| Structural Features: | SINGLE STRAND, OPEN |
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| Nucleic Acid Sequence: |
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| Primary Citation: | Vijay-Kumar, S., Sakore, T.D., Sobell, H.M.
Structure of a Novel Drug-Nucleic Acid Crystalline Complex: 1,10-Phenanthroline-Platinum(II) Ethylenediamine-5'-Phosphoryl-Thymidylyl(3'-5') Deoxyadenosine
J.Biomol.Struct.Dyn.
, 2,
pp. 333 - 344, 1984.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
P
1
21
1
|
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| Cell Constants: |
| a = 10.200 | b = 24.740 | c = 21.060 | (Ångstroms) |
 = 90.00 |  = 94.60 |  = 90.00 | (degrees) |
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| Crystallization Conditions: |
| Method: | | VAPOR DIFFUSION |
| Drop: | | WATER, MPD |
| Reservoir: | | WATER, MPD |
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| Refinement: |
The R value is
12.8
for 2367 reflections
in the resolution of 1.100
with I > 2.500 sigma(I).
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