 | | | |
| Title: | | INTERACTIONS BETWEEN AN ANTHRACYCLINE ANTIBIOTIC AND DNA MOLECULAR STUCTURE OF DAUNOMYCIN COMPLEXED TO D(CPGPTPAPCPG) AT 1.2-ANGSTROMS RESOLUTION | |
|
| Molecular Description: | 5'-D(CpGpTpApCpG)-3'
DAUNOMYCIN |
 |
| Structural Features: | RH DOUBLE HELIX |
|
| Nucleic Acid Sequence: |
| | | |
| Chain | A: | | (DC) (DG) (DT) (DA) (DC) (DG) |
|
|
| Primary Citation: | Wang, A.H., Ughetto, G., Quigley, G.J., Rich, A.
Interactions between an anthracycline antibiotic and DNA: molecular structure of daunomycin complexed to d(CpGpTpApCpG) at 1.2-A resolution.
Biochemistry
, 26,
pp. 1152 - 1163, 1987.
|
|
| | | |
| Experimental Information: | X-RAY DIFFRACTION |
|
| Space Group: |
P
41
21
2
|
|
| Cell Constants: |
| a = 27.860 | b = 27.860 | c = 52.720 | (Ångstroms) |
 = 90.00 |  = 90.00 |  = 90.00 | (degrees) |
|
|
| Refinement: | The structure was refined using the NUCLSQ program.
The R value is
17.5
for 5133 reflections
in the resolution range 10.000 to
1.180 Ångstroms
with Fobs > 3.000 sigma(Fobs).
|
|
|
