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| Title: |  | DNA-DRUG INTERACTIONS: THE CRYSTAL STRUCTURE OF D(CGATCG) COMPLEXED WITH DAUNOMYCIN |  |
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| Molecular Description: | 5'-D(CpGpApTpCpG)-3' DAUNOMYCIN |
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| Structural Features: | RH DOUBLE HELIX |
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| Nucleic Acid Sequence: |
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| Chain | A: | | (DC) (DG) (DA) (DT) (DC) (DG) |
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| Primary Citation: | Moore, M.H., Hunter, W.N., d'Estaintot, B.L., Kennard, O.
DNA-drug interactions. The crystal structure of d(CGATCG) complexed with daunomycin.
J.Mol.Biol.
, 206,
pp. 693 - 705, 1989.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
P
41
21
2
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| Cell Constants: |
| a = 27.980 | b = 27.980 | c = 52.870 | (Ångstroms) |
= 90.00 | = 90.00 | = 90.00 | (degrees) |
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| Refinement: | The structure was refined using the NUCLSQ program.
The R value is
25.0
for 1845 reflections
in the resolution range 10.000 to
1.500 Ångstroms
with Fobs > 5.000 sigma(Fobs).
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