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| Title: |  | TERNARY INTERACTIONS OF SPERMINE WITH DNA: 4'-EPIADRIAMYCIN AND OTHER DNA: ANTHRACYCLINE COMPLEXES |  |
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| Molecular Description: | 5'-D(CpGpApTpCpG)-3' 4'-EPIADRIAMYCIN |
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| Structural Features: | RH DOUBLE HELIX |
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| Nucleic Acid Sequence: |
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| Chain | A: | | (DC) (DG) (DA) (DT) (DC) (DG) |
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| Primary Citation: | Williams, L.D., Frederick, C.A., Ughetto, G., Rich, A.
Ternary interactions of spermine with DNA: 4'-epiadriamycin and other DNA: anthracycline complexes.
Nucleic Acids Res.
, 18,
pp. 5533 - 5541, 1990.
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| Experimental Information: | X-RAY DIFFRACTION |
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| Space Group: |
P
41
21
2
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| Cell Constants: |
| a = 28.040 | b = 28.040 | c = 53.150 | (Ångstroms) |
= 90.00 | = 90.00 | = 90.00 | (degrees) |
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| Refinement: | The structure was refined using the PROLSQ (MODIFIED BY G.J.QUIGLEY) program.
The R value is
19.6
for 1714 reflections
in the resolution range 10.000 to
1.500 Ångstroms
with Fobs > 1.500 sigma(Fobs).
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