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| Title: | | FORMALDEHYDE CROSS-LINKS DAUNORUBICIN AND DNA EFFICIENTLY: HPLC AND X-RAY DIFFRACTION STUDIES | |
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| Molecular Description: | 5'-D(CpGpCp(G49)pCpG)-3'
DAUNORUBICIN (DAUNOMYCIN) |
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| Structural Features: | RH DOUBLE HELIX |
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| Nucleic Acid Sequence: |
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| Chain | A: | | (DC) (DG) (DC) (G49) (DC) (DG) |
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| Primary Citation: | Wang, A.H., Gao, Y.G., Liaw, Y.C., Li, Y.K.
Formaldehyde cross-links daunorubicin and DNA efficiently: HPLC and X-ray diffraction studies.
Biochemistry
, 30,
pp. 3812 - 3815, 1991.
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| Experimental Information: | X-RAY DIFFRACTION |
|
| Space Group: |
P
41
21
2
|
|
| Cell Constants: |
| a = 27.943 | b = 27.943 | c = 52.243 | (Ångstroms) |
 = 90.00 |  = 90.00 |  = 90.00 | (degrees) |
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| Refinement: | The structure was refined using the NUCLSQ program.
The R value is
18.5
for 2229 reflections
in the resolution of 1.500
with Fobs > 3.000 sigma(Fobs).
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